News

6.1.2017 – Kelly’s manuscript, Methyllysine Binding Domains: Structural Insight and Small Molecule Probe Development is published in European Journal of Medicinal Chemistry.

3.1.2017 – Divya Chennamadhavuni joins the Hadden lab as a postdoctoral researcher. Welcome Divya!!!

2.1.2017 – RC’s manuscript, A Molecular Dynamics Approach to Identify an Oxysterol-Based Hedgehog Pathway Inhibitor, is published in Biochimica et Biophysica Acta – General Subjects.

12.5.2016 – Kaitlyn was named the December/January UConn School of Pharmacy Student Researcher of the Month. Congratulations Kaitlyn !!!

11.1.2016 – Jiachen Wen joins the Hadden lab as a postdoctoral researcher. Welcome Jiachen!!!

8.1.2016 – Angela Zaino joins the Hadden lab as a graduate student. Welcome Angela!!!

7.20.2016 – Kyle and Dmitry’s review on targeting translesion synthesis for anti-cancer drug development is published in Journal of Medicinal Chemistry.

5.25.2016 – Jen Pace is awarded an ACS Medicinal Chemistry Division Predoctoral Fellowship. Congratulations Jen!!!

5.23.2016 – Zuleyha Ozen joins the Hadden lab as a Research Technician. Welcome Zuleyha!!!

5.12.2016 – Jen and Al’s manuscriptRepurposing the Clinically Efficacious Antifungal Agent Itraconazole as an Anticancer Chemotherapeutic, is published in Journal of Medicinal Chemistry.

4.15.2016 – Chad’s manuscript, Synthesis and Evaluation of Osteogenic Oxysterols as Hedgehog Pathway Activators, is published as the highlighted front cover article in ChemMedChem.

3.15.2016 – RC Dash joins the Hadden lab as a new Postdoctoral Researcher. Welcome RC!!!

1.15.2016 – Kaitlyn McCarthy joins the Hadden lab as an undergraduate/Pharmacy student researcher.

12.18.2015 – Kelly Chan was named a UConn University Scholar. Congratulations Kelly!!!

12.1.2015 – Chad and Jen’s review article has been published in Current Medicinal Chemistry.

11.2.2015 – Kelly Teske joins the Hadden lab as a new Postdoctoral Researcher. Welcome Kelly!!!

10.1.2015 – Kelly Chan received the inaugural Antipas Family Research Scholarship in the UConn School of Pharmacy. Congratulations Kelly!!!

8.1.2015 – The Hadden lab has been awarded a grant from the National Science Foundation to explore the mechanisms through which calcitriol regulates Hh signaling during embryonic development.

3.13.2015 – Kelly has been awarded a UConn SURF Award for Summer 2015. Congratulations Kelly!!!

2.20.2015 – Al’s manuscript, Vitamin D3 Analogues that Contain Modified A- and Seco-B-Rings as Hedgehog Pathway Inhibitors, has been published in European Journal of Medicinal Chemistry.

1.20.2015 – Raymond Tran joins the Hadden lab as an undergraduate/Pharmacy student researcher.

12.29.2014 – Upasana’s manuscript, Design, Synthesis, and Evaluation of Hybrid Vitamin D3 Side Chain Analogues as Hedgehog Pathway Inhibitors, has been published in Bioorganic and Medicinal Chemistry.

12.12.2014 – In collaboration with Robert Wechsler-Reya, the Hadden lab has received a grant from the National Institutes of Health to develop itraconazole analogues as hedgehog pathway inhibitors for the treatment of medulloblastoma.

12.11.2014 – Evrett Thompson was named to the UConn University Scholars Program. Congratulations Evrett!!!

9.19.2014 – Upasana successfully defends her Ph.D dissertation. Congratulations Upasana!!!

8.28.2014 – Kelly Chan joins the Hadden lab as an undergraduate/Pharmacy student researcher.

8.01.2014 – Upasana and Kyle’s review, Recent Advances in the Design of Hedgehog Pathway Inhibitors for the Treatment of Malignancies, has been published in Expert Opnion on Drug Discovery.

5.8.2014 – Hadden lab research on Vitamin D3 analogues that target the Hh signaling pathway has been highlighted in an article on the American Cancer Society website.

4.29.2014 – Dan Raccuia was awarded a Pharm.D. Research Grant from the UConn School of Pharmacy for Summer/Fall 2014. Congratulations Dan!!!

4.14.2014 – Al’s manuscript, Structure-Activity Relationships for Vitamin D3-Based A-Ring Analogues as Hedgehog Pathway Inhibitors, has been published in Journal of Medicinal Chemistry.

1.20.2014 – Evrett Thompson joins the Hadden lab as an undergraduate researcher.

1.03.2014 – Kyle’s manuscript, Hedgehog Pathway Agonism: Therapeutic Potential and Small-Molecule Development, has been published in ChemMedChem.

12.19.2013 – Audrey Corman was awarded her second Pharm.D. Research Grant from the UConn School of Pharmacy for Spring 2014. Congratulations Audrey!!!

9.2.2013 – Al’s manuscript, Analogues of the Inhoffen-Lythgoe Diol with Anti-Proliferative Sctivity, has been published in Bioorganic and Medicinal Chemistry Letters.

8.26.2013 – In collaboration with Dmitry Korzhnev at UCHC, the Hadden lab received a CICATS Pilot Grant for a project titled “Translesion Synthesis DNA Polymerases as Targets for Anti-Cancer Drug Design.”

8.15.2013 – Al’s manuscript, Identification of Vitamin D3-Based Hedgehog Pathway Inhibitors That Incorporate an Aromatic A-Ring Isostere, has been published in ACS Medicinal Chemistry Letters.

7.1.2013 – Chad Maschinot and Jennifer Pace join the Hadden lab as new graduate students in Medicinal Chemistry

6.01.2013 – Dan Raccuia joins the Hadden lab as an undergraduate researcher.

3.25.2013 – The Hadden lab was awarded an American Cancer Society Research Scholar Award for a project titled “Vitamin D3 Analogues as Hedgehog Pathway Inhibitors.”

3.15.2013 – Dan Madden received a 2013 Summer Undergraduate Research Fellowship from UConn. Congratulations Dan!!!

3.12.2013 – Michele was named Student Researcher of the Month in the School of Pharmacy for March. Congratulations Michele!!!