Our collaborative manuscript with the Cantor lab at UMass Medical School, Inhibition of Translesion Synthesis Polymerase Rev1 exploits Replication Gaps as a Cancer Vulnerability, is published in Science Advances.

Kyle and Angela’s manuscript, Introduction to Medicinal Chemistry: A Five-Day Course for High School Students, is published in Journal of Chemical Education.

Seema receives a Summer Undergraduate Research Fellowship (SURF) from UConn for Summer 2020

A collaborative R01 grant with Sharon Cantor at UMass Medical School has been funded by the NIH/NCI.

Angela’s manuscript, Probing the Protein-Protein Interaction Between the ATRXADD Domain and the Histone H3 Tail, is published in Molecules

Jiachen’s manuscript, Inhibition of Hedgehog Signaling by Sterochemically Defined Des-Triazole Itraconazole Analogues, is published in Bioorganic & Medicinal Chemistry Letters

Jen’s manuscript, Formulation and Evaluation of Itraconazole Liposomes for Hedgehog Pathway Inhibition, is published in Journal of Liposome Research.

In collaboration with the White lab in the Department of Molecular and Cellular Biology at UConn, the Hadden lab has received a SPARK award to explore the antiviral activity of itraconazole and related analogues developed in the lab.

Kyle joins the Editorial Board of the Bioorganic Chemistry Section of Molecules

Jiachen’s manuscript, Truncated Itraconazole Analogues Exhibiting Potent Anti-Hedgehog Activity and Improved Drug-Like Properties, is published in ACS Medicinal Chemistry Letters