Kelly Chan joins the Hadden lab as an undergraduate/Pharmacy student researcher.

Upasana and Kyle’s review, Recent Advances in the Design of Hedgehog Pathway Inhibitors for the Treatment of Malignancies, has been published in Expert Opinion on Drug Discovery.

Hadden lab research on Vitamin D3 analogues that target the Hh signaling pathway has been highlighted in an article on the American Cancer Society website.

Dan Raccuia was awarded a Pharm.D. Research Grant from the UConn School of Pharmacy for Summer/Fall 2014. Congratulations Dan!!!

Al’s manuscript, Structure-Activity Relationships for Vitamin D3-Based A-Ring Analogues as Hedgehog Pathway Inhibitors, has been published in Journal of Medicinal Chemistry.

Evrett Thompson joins the Hadden lab as an undergraduate researcher.

Kyle’s manuscript, Hedgehog Pathway Agonism: Therapeutic Potential and Small-Molecule Development, has been published in ChemMedChem.

Audrey Corman was awarded her second Pharm.D. Research Grant from the UConn School of Pharmacy for Spring 2014. Congratulations Audrey!!!

Al’s manuscript, Analogues of the Inhoffen-Lythgoe Diol with Anti-Proliferative Activity, has been published in Bioorganic and Medicinal Chemistry Letters.

In collaboration with Dmitry Korzhnev at UCHC, the Hadden lab received a CICATS Pilot Grant for a project titled “Translesion Synthesis DNA Polymerases as Targets for Anti-Cancer Drug Design.”